Developed a novel photo-activated glycosylation method
Developed a novel photo-irradiation process utilizing glycosyl and benzhydryl phosphonium ions, achieving the first documented product yield through SN2-like substitution in the laboratory.
Facilitated glycosidic bond formation independent of external catalysts or reagents, thereby promoting advancements in green chemistry practices.
Validated product formation through high-performance liquid chromatography (HPLC) and mass spectrometry; employed Laser Flash Photolysis to monitor real-time mechanistic behavior.
Engineered fluorene-based glycosyl donors, enhancing efficient fluoride release and acceptor activation upon UV exposure, and fluorene per glucopyranoside were synthesized to expand the method's scope for photoglycosylation.
Developed a novel method for photo-induced hydrogel, enabling spatiotemporal control with enhanced reactivity, selectivity, and water solubility.
Synthesized and purified small molecule precursor to Photo-SPAAC linker: Sondheimer diyne.
Synthesized azide handles for modification of biocompatible polymers. FT-IR, MALDI-TOF, and elemental analysis to confirm success of modification.
Performed UV-Vis studies of photo onset of gelation, kinetics studies for rate of gelation, MALDI-TOF, SEM to characterize porosity and mechanical properties.
Performed HPLC, GC-MS analysis to confirm crosslinking between the Photo-SPAAC linker and modified polymer.
Graduate Student Research Assistant
Hines Lab, Department of Chemistry, UGA
Athens
01.2022 - 07.2022
Analyzed lipidomic data obtained by HILIC analysis to identify cell wall lipids that cause an increase in resistance to antibiotics in resistant bacterial strains.
Confirmed by studying extracted cell wall lipids by RPLC analysis.
Intern
Zydus Healthcare Limited
Ahmedabad
10.2018 - 12.2018
Assisted scientists in testing the stability of asthma drugs by conducting HPLC analysis of impurities and assays.
Learned wet-lab techniques, method optimization, selection of mobile phase, buffer, and diluent.
Education
Master of Science - Chemistry
University of Georgia
01.2026
Master of Science - Organic Chemistry
Gujarat University
01.2019
Bachelor of Science - Chemistry
Gujarat University
01.2017
Skills
Organic Synthesis
Photocleavable Compound Design
Kinetics studies
Carbohydrate Synthesis
Chromatography
Liquid Chromatography-Mass Spectrometry
UV/Vis and Fluorescence Spectroscopy
HPLC
MALDI-TOF
GC-MS
PH meter
Scanning Electron Microscopy
Nuclear Magnetic Resonance
Reversed Phase Liquid Chromatography Ion Mobility Mass Spectrometry
Hydrophilic Interaction Liquid Chromatography
Karl Fischer Titration
Dissolution Testing
Experiment Design
Analytical interpretation
Compound Characterization
Project Tracking
Data Interpretation
Presentations
Buffer and Solvent System Selection
Hazardous waste management (BSL2 curriculum)
Laboratory Chemicals management
Microsoft Office
C language (Intermediate)
Linux
Chimera
Origin
MATLAB
Chemdraw
Skyline
Progenesis
Leadership Services
Chemistry Grad Student Organization, Department of Chemistry, UGA, Athens, GA, Community Service Chair, 09/21, 05/25, Organized Boy Scout Events: Advance-a-rama, Chemistry MB 2022 - 2024, Volunteered for Gen Chem-1 American Chemical Society review session 2021, Volunteered at the Athens-Clarke County animal shelter 2021
Department of Chemistry, GA & S College, Gujarat University, Ahmedabad, India, Organized a state-level seminar on 'Emerging Trends and Advances in Chemistry' 2017
Awards
Outstanding Teaching Assistant Award, University of Georgia, 2025
Field Technician Networking And Storage (ELE/Q4606), Skill India, Gov. of India, 2019
Presentations
Designing a biocompatible hydrogel by Alginate SPAAC and photo-SPAAC crosslinking, Shivani R. Nagode
Chen Zhao, Christopher J. Molnar, Vladimir V. Popik, 75th Southeastern Regional Meeting of the American Chemical Society, Photoactive Materials and Devices for Energy Storage and Beyond, Atlanta, GA, 10/24, Lipoteichoic acid synthase enzyme inhibition as a novel approach to study daptomycin-resistant pathogens, Shivani Nagode
Kelly M. Hines, 70th American Society for Mass Spectrometry Conference on Mass Spectrometry and Allied Topics, Minneapolis, MN, 06/22, En Route to Photo-Glycosylation: Light-induced SN1 and SN2 Reactions, Shivani Nagode, Pallabita Basu, Shrey Patel, Emanuel Nekongo, David Crich, Vladimir Popik
31st Inter - American Photochemical Society, Miramar Beach, FL, 01/24, En Route to Photo-Glycosylation: Light-induced SN1 and SN2 Reactions, Shivani Nagode, Pallabita Basu, Shrey Patel, David Crich, Vladimir Popik
Symposium on Caged Compounds by the Institute of Organic Chemistry and Biochemistry (IOCB) of the Czech Academy of Sciences, Prague, Czech Republic, 06/24